Urea-hydrogen peroxide/silica phosphoric acid-catalyzed oxidation- condensation Tandem reaction: One-pot synthesis of 2-substituted benzimidazoles from alcohols
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Abstract:
An efficient one-pot oxidation/condensation tandem process has been developed for the synthesis of 2-substituted benzimidazole derivatives from benzylic alcohols and 1,2-phenylenediamine with use of urea-hydrogen peroxide/silica phosphoric acid as a bifunctional catalyst. This method provides a rapid and efficient access to 2-substituted benzimidazoles.
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urea-hydrogen peroxide/silica phosphoric acid-catalyzed oxidation- condensation tandem reaction: one-pot synthesis of 2-substituted benzimidazoles from alcohols
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Journal title
volume 2 issue 3
pages 141- 145
publication date 2012-09-01
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